Sunday, May 27, 2018

The long and the short of DNA replication

An unexpected two-step mechanism occurs when cells copy DNA.

‚ÄčThe process of copying DNA is complex choreography that requires rapid speeds and pin-point precision. Discovering the intricate details of this process could identify new ways to target diseases, such as cancer, and KAUST scientists have just uncovered a crucial step.

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Image: KAUST scientists, including first author Manal Zaher, discovered that the enzyme FEN1 acts as a switch during DNA replication.