KAUST scientists see the first steps of life in DNA unwinding

24 March, 2025

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life. A new study from King Abdullah University of Science and Technology (KAUST), published in Nature, captures the moment DNA begins to unwind, allowing for all the events that follow in DNA replication. This direct observation sheds light on the fundamental mechanisms that allow cells to faithfully duplicate their genetic material, a cornerstone for growth and reproduction. 

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