Apr 2022
Host: Professor Charlotte Hauser
Abstract:
Despite
the success of a handful of companies and the overabundance of research
the tissue engineering & regenerative medicine (TE&RM)
community has still not delivered the more then 3 decades ago promised
health care and commercial break through's. Yet, translation of research
results into clinical application is still the rallying cry of the
modern TE&RM establishment. Translating observations from
fundamental experimental research protocols (e.g., in vitro, ex vivo, in
vivo, or in silico,etc.) to address into not even clinical routines but
first in human studies has diverse challenges. Using previous
publications uncritically to justify further research, regardless of
their veracity, relevance, robustness or quality, is often the most
rapid route to write and fund grant proposals and to obtaining
publishable data, even though these data may have no translational and
often even scientific relevance. The research data manufacturing
machinery is authorised but real world applicability and impact are
often compromised. Low translational success rates continue to plague
most aspects of TE&RM research as the development of bedside to
bench and back again approach possess challenges that most academics but
also TE&RM companies are not typically trained to overcome. Based
on the above arguments this talk will critically review two key research
areas in TE&RM, namely bioprinting and scaffold guided tissue
engineering.
Bio:
Professor's
Hutmacher scholarly track record illustrate successful mastery of a
major challenge in an interdisciplinary field: the ability to transcend
traditional disciplinary boundaries, to initiate and nurture excellent
research and educational programs across different disciplines. This was
achieved through an interdisciplinary research program via convergence
of science & engineering (bioengineering, biomaterials science,
computational modelling, chemistry and nanotechnology), the life science
disciplines (molecular & cell biology, stem cell research,genomics,
proteomics, bioinformatics), and clinical research (orthopedics,
plastic and reconstructive surgery, radiology). He is one of the few
academics who successfully translated tissue engineering research
programs from fundamental research to routine clinical application.