28

Nov 2024

PhD Dissertation Defense

Self-Assembled Supramolecular Nanostructures for Biological Imaging and Delivery

Presenter
Dana Kelabi
Date
28 Nov, 2024
Time
10:30 AM – 12:00 PM

Abstract:
This dissertation explores the design and applications of supramolecular and hybrid materials in biological systems. 
Project 1 investigates the tautomeric organic cage (OC1) for fluorescent microscopy, demonstrating its high cell permeability and selective mitochondrial targeting, enabling single-molecule visualization in live cells. 
Project 2 focuses on the biocompatible Mg mucicate (MUM) coordination polymer, which efficiently delivers therapeutic proteins and genetic materials, including successful CRISPR/Cas9 delivery. 
Finally, Project 3 presents the SmartCube system, a core-shell drug delivery platform for oral vitamin D3, designed to improve absorption of vitamin D and promote bone health. 
Overall, this research highlights the significant advancements and potential applications of supramolecular materials in medicine.

Bio:
Dana Al Kelabi’s doctoral research at KAUST, under Prof. Niveen Khashab's guidance, focuses on pioneering approaches to revolutionize biomedical applications. Dana's contributions have been recognized through publications in prestigious journals and presentations at renowned conferences. She is proficient in molecular biology techniques, and advanced imaging technologies.
Master of Science, Bioscience, KAUST | Thuwal, KSA, 2020
Bachelor of Pharmaceutical Sciences, KSU | Riyadh, KSA, 2018
Research Interests:
Design and synthesis of supramolecular porous materials for targeted biological imaging and drug delivery.
Exploration of innovative approaches to harness the unique properties of nanostructures in biomedical applications.
Aim to facilitate the precise and efficient delivery of therapeutics for improved biomedical outcomes.

Event Quick Information

Date
28 Nov, 2024
Time
10:30 AM - 12:00 PM
Venue
Auditorium between buildings 4 & 5