Advanced bioprinting leads to 3D brain models

27 September, 2023

Neurodegenerative diseases such as Parkinson’s disease are hard to study due to the complexity of the human brain, the difficulty of substituting native tissues with functional, in-vitro models and the challenges of obtaining human specimens.

3D bioprinting offers a new way for scientists to create 3D models that can overcome these hurdles, but finding suitable biomaterials that can accommodate neurons in 3D is not easy.

In a notable achievement at Charlotte Hauser’s laboratory in KAUST, postdoc Sherin Abdelrahman has established 3D models of brain organoids based on 3D scaffolds composed of ultrashort self-assembling peptides that contain nothing more than four amino acids.

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