Malaria protein discovery offers path for novel antimalarial intervention strategies

25 October, 2023

The discovery of a malaria protein that helps the parasite grow inside red blood cells and plays a key regulatory role in the parasite’s immune evasion tactics could pave the way for new vaccines or therapeutics to combat the deadly infection.

The protein, known as PfAP2-P, was previously identified in a KAUST-led study that explored malarial genes and proteins displaying rhythmic 24-hour expression patterns — an adaptation that allows the parasite to synchronize its activities with those of the host during the human blood stage of its developmental cycle.

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